The Kaimoor Wildlife Sanctuary is a serene forested area located around 100 km from Varanasi. Spread over an area of 1,342 sq km, the sanctuary is dotted with several waterfalls, of which the finest are, Karkat and Telhar falls. The sanctuary is most famous for its blackbuck population and is home to several other animals like tiger, leopard, wild boar, sloth bear, sambar deer, chital, four-horned antelope and nilgai. Apart from these, crocodiles, pythons and other different species of snakes are also found. The place is a paradise for birdwatchers who can spot more than 70 species of resident birds during the year, along with many migratory birds. Some of the common bird species that one can find here are the brahmini duck, pintail, red-crested poacher, coot, common teal, mallard and tufted duck. Visitors can go up to watchtowers or to the waterholes to get good views.

The sanctuary was established in 1982 and also houses a sheer diversity of vegetation, including tree vegetation like baakli, mahua, dhaak and bamboo. It is one of the major tourist attractions that is located on the border of Bihar and Uttar Pradesh. The topography of the region comprises deciduous forests, swampy marshes and grasslands. Moreover, it has caves with prehistoric paintings and a fossil park that are unique to it.